Why We Age - The Cross-Linking Theory
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May 02, 2007 |
The Cross-Linking Theory
Also referred to as the Glycosylation Theory of Aging.
In this theory it is the binding of glucose (simple sugars) to protein, a process that occurs under the presence of oxygen. Once this binding has occurred the protein becomes impaired and is unable to perform as efficiently. Known cross-linking disorders include senile cataract and the appearance of tough, leathery and yellow skin. Diabetics have 2-3 times the numbers of cross-linked proteins than healthy individual. Cross linked proteins are responsible for cardiac enlargement and the hardening of collagen, which lead to the increased susceptibility of a cardiac arrest. Cross linked proteins have also been implicated in renal disorders. Sugars binding to DNA may cause damage that leads to malformed cells and thus cancer.Labels: anti-aging |
posted by Maggie @ 7:25 am   |
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